| 11-02-2005 | Wed | Northern State (exh.) (FSN#) | Lexington, Ky. | W, 80-51 |
| 11-09-2005 | Wed | Georgetown (Ky.) (exh.) (FSN/BBSN) | Lexington, Ky. | W, 85-63 |
| 11-13-2005 | Sun | South Dakota State (ESPNU#) | Lexington, Ky. | W, 71-54 |
| 11-14-2005 | Mon | Lipscomb (ESPNU#) | Lexington, Ky. | 08:00 pm |
| 11-21-2005 | Mon | TBA (Guardians Classic) (ESPN2) | Kansas City, Mo. | TBA |
| 11-22-2005 | Tue | TBA (Guardians Classic) (ESPNU or ESPN2) | Kansas City, Mo. | TBA |
| 11-25-2005 | Fri | Liberty (FSN#) | Lexington, Ky. | 07:00 pm |
| 11-29-2005 | Tue | High Point (FSN#) | Lexington, Ky. | 07:00 pm |
| 12-03-2005 | Sat | North Carolina (CBS) | Lexington, Ky. | 12:00 pm |
| 12-06-2005 | Tue | Georgia State (ESPNU) | Atlanta, Ga. | 08:00 pm |
| 12-10-2005 | Sat | Indiana (CBS) | Indianapolis, Ind. | 03:45 pm |
| 12-17-2005 | Sat | Louisville (CBS) | Lexington, Ky. | 02:00 pm |
| 12-23-2005 | Fri | Iona (FSN#) | Louisville, Ky. | 07:00 pm |
| 12-30-2005 | Fri | Ohio (ESPN2) | Cincinnati, Ohio | 08:00 pm |
| 01-03-2006 | Tue | Central Florida (FSN#) | Lexington, Ky. | 07:00 pm |
| 01-07-2006 | Sat | Kansas (ESPN) | Lawrence, Kan. | 12:00 pm |
| 01-10-2006 | Tue | Vanderbilt (ESPN) | Lexington, Ky. | 09:00 pm |
| 01-14-2006 | Sat | Alabama (CBS) | Lexington, Ky. | 01:00 pm |
| 01-17-2006 | Tue | Georgia (ESPN) | Athens, Ga. | 09:00 pm |
| 01-21-2006 | Sat | South Carolina (JP) | Lexington, Ky. | 01:00 pm |
| 01-24-2006 | Tue | Auburn (ESPN) | Auburn, Ala. | 07:00 pm |
| 01-29-2006 | Sun | Arkansas (CBS) | Lexington, Ky. | 01:00 pm |
| 02-01-2006 | Wed | Mississippi State (JP) | Starkville, Miss. | 08:00 pm |
| 02-04-2006 | Sat | Florida (ESPN2) | Gainesville, Fla. | 09:00 pm |
| 02-07-2006 | Tue | Tennessee (ESPN) | Lexington, Ky. | 07:00 pm |
| 02-11-2006 | Sat | Vanderbilt (JP) | Nashville, Tenn. | 03:00 pm |
| 02-15-2006 | Wed | Georgia (JP) | Lexington, Ky. | 08:00 pm |
| 02-18-2006 | Sat | South Carolina (CBS) | Columbia, S.C. | 01:30 pm |
| 02-22-2006 | Wed | Ole Miss (JP) | Lexington, Ky. | 08:00 pm |
| 02-25-2006 | Sat | LSU (CBS) | Baton Rouge, La. | 03:45 pm |
| 03-01-2006 | Wed | Tennessee (JP) | Knoxville, Tenn. | 08:00 pm |
| 03-05-2006 | Sun | Florida (CBS) | Lexington, Ky. | 12:00 pm |
| 03-09-2006 | Thu | SEC Tournament | Nashville, Tenn. | TBA |
| 03-10-2006 | Fri | SEC Tournament | Nashville, Tenn. | TBA |
| 03-11-2006 | Sat | SEC Tournament | Nashville, Tenn. | TBA |
| 03-12-2006 | Sun | SEC Tournament | Nashville, Tenn. | TBA |
# Delayed TV on Big Blue Sports Network
