Rubbertown is Louisville, Kentucky's neighborhood of heavy industrial manufacturing plants, and is located near a power plant and a toxic landfill site. These facilities are adjacent to residential neighborhoods.

The documentary Rubbertown follows Louisville, Kentucky resident Monika Burkhead as she tries to move her entire house to another county after suffering through years of regular leaks, spills, and occasional explosions at the nearby facilities, alongside fellow residents reporting higher rates of cancer and respiratory illnesses.